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Meth 10mg Tablet

Generic: Methotrexate

Type: Tablet

Pack Size: 14 pcs

Meth 10mg Tablet contains Methotrexate, which hinders the rapid reproduction of cells in the body, acting as an anti-tumor agent. It suppresses the body's immune response, serving as an effective immunosuppressant. The medication also displays anti-inflammatory effects, reducing pain, swelling, and redness. Consequently, it effectively addresses symptoms associated with conditions like rheumatoid arthritis and psoriasis.


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Discount Price: ৳ 163.4
MRP: ৳ 172 5% Off

⪼ Save  ৳: 8.6  in this Product


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✅ Description:

Meth 10mg Tablet is categorized as an 'anti-metabolite and immunosuppressant' medication. It is employed in the treatment of various conditions:

Active Rheumatoid Arthritis and Polyarticular Juvenile Rheumatoid Arthritis:

  • Used alone or in combination with other drugs to treat active rheumatoid arthritis, including the polyarticular juvenile form. It mitigates inflammation in joint tissues, reducing pain, and inflammation, and delaying joint damage.

Psoriasis and Severe Psoriatic Arthritis:

  • Employed to treat severe psoriasis and psoriatic arthritis by suppressing the overactive immune system responsible for these conditions.

Cancer Treatment:

  • Used, either alone or in combination with other medications, to treat breast cancer, lung cancer, head and neck cancer, mycosis fungoides (a type of blood cancer), and advanced-stage non-Hodgkin's lymphomas. It hinders the growth of cancer cells.

Meth 10mg Tablet, containing 'Methotrexate,' functions by interrupting immune system processes causing inflammation, providing relief in joint conditions, and preventing the growth of cancer cells.

It is crucial to adhere to the prescribed dosage, as daily intake may lead to serious toxic effects. Pregnant or breastfeeding individuals should avoid Meth 10mg Tablet. Caution is advised while driving due to possible dizziness and fatigue. Alcohol consumption should be avoided during treatment. Regular blood, kidney, and liver tests may be recommended for monitoring. Inform your doctor about medications and health conditions to prevent potential side effects or interactions.

Safety Advices


Alcohol
UNSAFE

It is recommended to avoid the consumption of alcohol while taking Meth 10mg Tablet as it may increase the risk of liver damage. Consult your doctor before taking Meth 10mg Tablet.


Pregnancy
UNSAFE

Meth 10mg Tablet is not recommended for use if you are pregnant and/or are planning to become pregnant since it can be harmful to the fetus (growing baby) and lead to various malformations. Consult your doctor before taking Meth 10mg Tablet.


Breastfeeding
UNSAFE

Meth 10mg Tablet is not recommended if you are a nursing mother. Consult your doctor before taking Meth 10mg Tablet.


Driving
UNSAFE

Meth 10mg Tablet is not recommended if you feel tired or dizzy after taking the medicine. Consult your doctor before taking Meth 10mg Tablet.


Kidney
CONSULT YOUR DOCTOR

Meth 10mg Tablet is not recommended if you have had a kidney disorder and/or are receiving any dialysis treatment. Consult your doctor before taking Meth 10mg Tablet.


Liver
CAUTION

Meth 10mg Tablet is not recommended if you have a liver disorder. Consult your doctor before taking Meth 10mg Tablet.

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✔️ Uses of Meth 10mg Tablet

Rheumatoid arthritis, Psoriatic arthritis, Psoriasis, Cancer

✔️ How does Meth 10mg Tablet work?

Meth 10mg Tablet works by suppressing the activity of the immune system and helps reduce pain and swelling. It also slows the growth of cancer cells. 

✔️ Side Effects of Meth 10mg Tablet
  • Nausea
  • Vomiting
  • Diarrhea
  • Unusual fatigue
  • Dizziness
  • Headache
  • Loss of appetite
  • Elevated liver enzymes
  • Lowered resistance to infections
  • Tingling sensation
  • Leukopenia (decreased number of white blood cells)
  • Soreness of mouth and lips
✔️ Quick Suggestions:
  • Meth 10mg Tablet can be taken with or without food. Do not break, chew, or crush the tablet.
  • Swallow the tablet as a whole with a sufficient amount of water.
  • Avoid taking more or less than the recommended dose. Take it at the same time every day for ease of remembering.
  • Avoid consumption of alcohol while taking this medicine, as it may increase the risk of liver problems.
  • Do not discontinue the tablet without consulting your doctor, as your condition may become worse.
  • Your doctor may suggest tests to monitor your blood cell count while you are taking this medicine.
  • Meth 10mg Tablet may suppress immune activity and increase the risk of infections. Hence avoid contact with people who have infections that may spread to others.
  • Meth 10mg Tablet may make your skin sensitive to sunlight. Hence avoid excessive sun exposure and wear protective clothing while stepping out in the sun.
✔️ Indications:

Meth 10mg Tablet is utilized in the treatment of various medical conditions:

  • Choriocarcinoma

Choriocarcinoma is a fast-growing cancer that occurs in a woman's uterus. Meth 10mg Tablet is used in the treatment of Choriocarcinoma.

  • Rheumatoid Arthritis

Rheumatoid arthritis (RA) is an autoimmune disorder that affects the small joints in the body causing pain and swelling. Meth 10mg Tablet is used to treat this condition along with other medicines and physical therapy.

  • Psoriasis

Psoriasis is an autoimmune skin condition characterized by red inflamed skin, often covered by scales. Meth 10mg Tablet is used to treat this condition.

  • Acute lymphoblastic Leukaemia (ALL) and Lymphoma

Methotrexate 2.5 MG Tablet is used in the treatment of certain cancers such as acute lymphoblastic leukemia (a type of blood cancer), and lymphoma (cancer that starts in the cells that are part of the body's immune system). It helps to inhibit the growth of cancer cells.

Acute Lymphoblastic Leukemia (ALL) and Lymphoma:

  • Meth 10mg Tablet is used in the treatment of certain cancers, including acute lymphoblastic leukemia (a type of blood cancer) and lymphoma (cancer originating in immune system cells). It works by inhibiting the growth of cancer cells.
✔️ Pharmacology:

Meth 10mg Tablet, classified as an 'anti-metabolite and immunosuppressant,' is employed in treating various conditions, including active rheumatoid arthritis, polyarticular juvenile rheumatoid arthritis, severe psoriasis, and severe psoriatic arthritis. Its pharmacological action involves interrupting immune system processes responsible for joint inflammation in rheumatoid and psoriatic arthritis, leading to pain reduction and inflammation alleviation. Additionally, Meth 10mg Tablet is used, either alone or in combination with other medications, to treat breast cancer, lung cancer, head and neck cancer, mycosis fungoides, and advanced-stage non-Hodgkin's lymphomas. Its mechanism involves interference with DNA production to prevent cancer cell growth. Meth 10mg Tablet may also find application in treating inflammatory bowel disease.

✔️ Dosage & Administration:

Administration Instructions:

Oral Administration:

  • Best taken on an empty stomach.
  • May be taken with meals to reduce gastrointestinal discomfort.
  • Avoid taking milk-rich products.

IV/IM Preparation:

  • Reconstitute with D5W or NS.
  • 20-mg vial: Up to 25 mg/mL.
  • 1-g vial: Up to 50 mg/mL.
  • Further dilution may be necessary for IV infusion.

IV/IM Administration:

  • Administer by IM, IV push, or IV infusion.
  • Regular IV: Given with no more than 25 mg/mL.
  • IV push: Administered at 10 mg/min.
  • IV infusion (>100 mg): Administered over 30 minutes to 4 hours, or according to institutional protocol.
  • High-dose therapy (uses 1-g vial): Administered over 4 hours.
  • Specific dosing schemes vary, but high doses should be followed by leucovorin 24 hours after initiation of therapy to prevent toxicity.

Adult Dose:

  • Oral (PO) Administration:
    • Choriocarcinoma: 15-30 mg/day for 5 days, repeat after at least 1 week for 3-5 courses.
    • Mycosis fungoides: 2.5-10 mg/day to induce remission.
    • Burkitt's lymphoma: 10-25 mg/day for 4-8 days, repeat after 7-10 days.
    • Rheumatoid arthritis: 7.5 mg once weekly, adjust if needed, up to 20 mg/week.
    • Crohn's disease: 12.5-22.5 mg once weekly for up to 1 year.

Intravenous (IV) Administration:

  • Psoriasis: 10-25 mg once weekly, adjust subsequent doses if needed.
  • Osteosarcoma: 12-15 g/m² as an infusion, followed by folinic acid.
  • Breast cancer: 10-60 mg/m² often with cyclophosphamide and fluorouracil.
  • Advanced lymphosarcoma: Up to 30 mg/kg, followed by folinic acid rescue.
  • Acute lymphoblastic leukemia Maintenance: 2.5 mg/kg every 14 days.

Intramuscular (IM) Administration:

  • Acute lymphoblastic leukemia Maintenance: 15 mg/m² 1-2 times/week with other agents.
  • Choriocarcinoma: 15-30 mg/day for 5 days. Repeat after at least 1 week for 3-5 courses.
  • Mycosis fungoides: 50 mg/week in 1-2 divided doses.
  • Crohn's disease: 25 mg once weekly for 16 weeks. Maintenance: 15 mg/week.

Intrathecal Administration:

  • Meningeal leukemia: 12 mg/m² (Max: 15 mg) once weekly for 2-3 weeks, then once monthly.

Hepatic Impairment:

  • Bilirubin 3.1-5.0 mg/dL or AST > 3 times ULN: Give 75% of the dose.
  • Bilirubin >5.0 mg/dL: Avoid use.

Child Dose:

Polyarticular Juvenile Idiopathic Arthritis:

  • Initial: 10 mg/m² PO/IM/SC once weekly.

Meningeal Leukemia:

  • <1 year: 6 mg intrathecally (IT) every 2-5 days.
  • 1-2 years: 8 mg IT every 2-5 days.
  • 2-3 years: 10 mg IT every 2-5 days.

3 years: 12 mg IT every 2-5 days.

Renal Dose:

Renal Impairment:

  • CrCl (ml/min) Dosage Recommendation:
    • 61-80: 75% of the dose.
    • 51-60: 70% of the dose.
    • 10-50: 30-50% of the dose.
    • <10: Avoid use.

Intermittent Hemodialysis:

  • 50% of the dose at normal dosing intervals.

Continuous Renal Replacement Therapy:

  • 50% of the dose at normal dosing intervals.
✔️ Interaction

Certain medications may interact with Meth 10mg Tablet, influencing its effectiveness, or Meth 10mg Tablet itself may impact the efficacy of other drugs if taken concurrently. It is crucial to inform your doctor about all the medicines, supplements, or herbal products you are currently using or plan to take to prevent potential interactions.

Special attention is warranted if you are taking medications for:

  1. Diabetes (e.g., metformin)
  2. Pain (e.g., phenylbutazone)
  3. Fluid accumulation (e.g., furosemide)
  4. Bacterial infection (e.g., tetracycline)
  5. Seizures (e.g., phenytoin)
  6. Cancer (e.g., doxorubicin)
  7. Gout (e.g., probenecid)
✔️ Contraindications

Do not take Meth 10mg Tablet if you:

  • Are allergic to any of its contents.
  • Have immunodeficiency conditions.
  • Experience bone marrow problems.
  • Have a low white blood cell count.
  • Have a low platelet count.
  • Suffer from serious anemia.
  • Have liver problems due to alcohol abuse or chronic liver disease.
  • Are pregnant or breastfeeding?
✔️ Pregnancy & Lactation

Pregnancy: Meth 10mg Tablet is not recommended during pregnancy due to potential harm to the developing fetus. Consult your doctor if you are pregnant.

Breastfeeding: Meth 10mg Tablet may pass into breast milk and cause serious side effects in your baby. Consult your doctor if you are breastfeeding.

✔️ Precautions & Warnings

Consult your doctor before taking Meth 10mg Tablet if you:

  • Have or had liver or kidney problems.
  • Experience ulceration in the stomach or bowels.
  • Are in poor general condition.
  • Have received any vaccinations or are due to have any vaccinations?
  • Have diabetes.
  • Experience ascites (fluid in the stomach area).
  • Have lung problems or fluid in the lungs.
✔️ Storage Conditions

Store Meth 10mg Tablet in a cool and dry place, away from direct sunlight. Keep out of reach of children and pets.

Frequently Asked Questions (FAQ)

Folic acid is required to make new cells in the body and Meth 10mg Tablet decreases the folic acid levels in the body. Folic acid can help reduce some of the common side effects of Meth 10mg Tablet such as mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia and liver problems.

Yes, Meth 10mg Tablet may affect fertility in both males and females. It may cause a decrease in sperm count in males and menstrual disturbances in females. No need to worry, these effects are reversible and disappear once the therapy is discontinued.

Yes, Meth 10mg Tablet can cause a sore mouth and mouth ulcers as side effects in some cases. Taking folic acid along with this medicine may help in reducing the ulcers. Ask your doctor if the dose can be reduced as dose reduction may further help in reducing the ulcers.
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Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
ePharma reserves the right to make adjustments to pricing, Products and Service offerings for reasons including, but not limited to, changing market conditions, Product discontinuation, Product unavailability, manufacturer price changes, supplier price changes and errors in advertisements. All orders are subject to Product availability and the availability of Personnel to perform the Services. Therefore, Seller cannot guarantee that it will be able to fulfill Customer’s orders. If Services are being performed on a time and materials basis, any estimates provided by Seller are for planning purposes only.

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